Mutant Name: irx2-1 (irregular xylem 2-1)

Gene Name IRX2
Protein Name endo-1,4-glucanase
Mutagen EMS
Category forward genetics
Organism Arabidopsis thaliana
Ecotype Lb
Donor
General Description 1.irx2-1 is an allele of korrigan. Pro-250 is altered to Leu.
2.It has a cellulose deficiency in the secondary cell wall with a decrease in stiffness of the stem material.
Organ Specificity 1.The inflorescence stem of irx2 mutant contains approximately 30% of the total crystalline cellulose of the wild type.
2. No decrease in cellulose was observed in the primary walls of cortical and epidermal cells of the stem.
Impact on Wall It has a role in the later stages of secondary cell wall formation, maybe in processing of the growing microfibrils or release of the cellulose synthase complex.
Impact on Sugar Composition The total crystalline cellulose in the inflorescence stem of irx2 mutant contains approximately 30% of the level of the wild type.
Reference 1.Szyjanowicz PM, McKinnon I, Taylor NG, Gardiner J, Jarvis MC, Turner SR. (2004) The irregular xylem 2 mutant is an allele of korrigan that affects the secondary cell wall of Arabidopsis thaliana. Plant J. Mar;37(5):730-40.

2.Turner, S.R. and Somerville, C.R. (1997) Collapsed xylem phenotype of Arabidopsis identifies mutants deficient in cellulose deposition in the secondary cell wall. Plant Cell, 9, 689-701.

3.Nicol F, His I, Jauneau A, Vernhettes S, Canut H, Hofte H. (1998) A plasma membrane-bound putative endo-1,4-beta-D-glucanase is required for normal wall assembly and cell elongation in Arabidopsis. EMBO J. Oct 1;17(19):5563-76.